Sequential respiratory syncytial virus and cytomegalovirus pneumonia following bone marrow transplantation
| Autor: | Elie Picard, Joseph Kapelushnik, Jayesh Mehta, Reuven Or, Arnon Nagler, G. Cividalli, Dan Engelhard, Yuval Brandstetter |
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| Rok vydání: | 1995 |
| Předmět: |
Human cytomegalovirus
Male Paramyxoviridae Histiocytosis Non-Langerhans-Cell Pneumonia Viral Congenital cytomegalovirus infection Respiratory Syncytial Virus Infections Lung injury medicine.disease_cause Herpesviridae Virology medicine Humans Bone Marrow Transplantation biology business.industry Respiratory disease Infant Familial Hemophagocytic Lymphohistiocytosis medicine.disease biology.organism_classification Pneumonia Infectious Diseases Immunology Cytomegalovirus Infections Female business |
| Zdroj: | Journal of medical virology. 46(2) |
| ISSN: | 0146-6615 |
| Popis: | A 6-month-old child with familial hemophagocytic lymphohistiocytosis (FHL) experienced early sequential pneumonia due to respiratory syncytial virus (RSV) and cytomegalovirus (CMV) following bone marrow transplantation (BMT). The patient was deficient in natural killer (NK) cell activity (as found frequently in patients with FHL), and this risk factor may have played a major role in the concomitant infection by the two viral pathogens. Rapid diagnostic methods for both viruses are essential and early specific treatment may serve to ameliorate RSV- and CMV-induced lung injury in these life-threatening infections. © 1995 Wiley-Liss, Inc. |
| Databáze: | OpenAIRE |
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