Correlation of minimum apparent diffusion coefficient with maximum standardized uptake on fluorodeoxyglucose PET-CT in patients with rectal adenocarcinoma
| Autor: | Geçim E, Küçük Nö, Erden A, Er Hç |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty Adenocarcinoma Multimodal Imaging Fluorodeoxyglucose F18 Region of interest medicine Rectal Adenocarcinoma Humans Effective diffusion coefficient Abdominal Imaging Radiology Nuclear Medicine and imaging Positron emission Aged Retrospective Studies medicine.diagnostic_test Rectal Neoplasms business.industry Magnetic resonance imaging Middle Aged Sagittal plane medicine.anatomical_structure Positron-Emission Tomography Coronal plane Female Radiology Tomography Radiopharmaceuticals Tomography X-Ray Computed Cardiology and Cardiovascular Medicine Nuclear medicine business |
| Zdroj: | Diagnostic and Interventional Radiology. |
| ISSN: | 1305-3612 1305-3825 |
| Popis: | PURPOSE The aim of this study was to retrospectively assess the correlation between minimum apparent diffusion coefficient (ADCmin) values obtained from diffusion-weighted magnetic resonance imaging (MRI) and maximum standardized uptake values (SUVmax) obtained from positron emission tomography-computed tomography (PET-CT) in rectal cancer. MATERIALS AND METHODS Forty-one patients with pathologically confirmed rectal adenocarcinoma were included in this study. For preoperative staging, PET-CT and pelvic MRI with diffusion-weighted imaging were performed within one week (mean time interval, 3±1 day). For ADC measurements, the region of interest (ROI) was manually drawn along the border of each hyperintense tumor on b=1000 s/mm2 images. After repeating this procedure on each consecutive tumor-containing slice to cover the entire tumoral area, ROIs were copied to ADC maps. ADCmin was determined as the lowest ADC value among all ROIs in each tumor. For SUVmax measurements, whole-body images were assessed visually on transaxial, sagittal, and coronal images. ROIs were determined from the lesions observed on each slice, and SUVmax values were calculated automatically. The mean values of ADCmin and SUVmax were compared using Spearman's test. RESULTS The mean ADCmin was 0.62±0.19×10-3 mm2/s (range, 0.368-1.227×10-3 mm2/s), the mean SUVmax was 20.07±9.3 (range, 4.3-49.5). A significant negative correlation was found between ADCmin and SUVmax (r=-0.347; P = 0.026). CONCLUSION There was a significant negative correlation between the ADCmin and SUVmax values in rectal adenocarcinomas. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|