Long-term hospitalization during pregnancy is a risk factor for vitamin D deficiency in neonates
| Autor: | Morihiro Iwata, Sayuri Matsumoto, Tetsu Takagi, Shigeo Nakajima, Masaaki Shima, Toshio Okano, Keiichi Ozono, Kumi Nishimura, Naoko Tsugawa, Toru Kanzaki, Yoko Santo, Yuki Kanda, Haruhiko Hirai |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Adult
medicine.medical_specialty Endocrinology Diabetes and Metabolism Physiology Gestational Age Breast milk Umbilical cord vitamin D deficiency Phosphates Endocrinology Pregnancy Reference Values Risk Factors Internal medicine medicine Vitamin D and neurology Humans Orthopedics and Sports Medicine Risk factor Calcifediol Milk Human business.industry Infant Newborn Gestational age General Medicine Fetal Blood Vitamin D Deficiency medicine.disease Hospitalization Pregnancy Complications medicine.anatomical_structure Cord blood Sunlight Calcium Female business |
| Zdroj: | Journal of Bone and Mineral Metabolism. 21:103-108 |
| ISSN: | 1435-5604 0914-8779 |
| DOI: | 10.1007/s007740300017 |
| Popis: | In order to examine the effects of long-term hospitalization during pregnancy on vitamin D metabolism in pregnant women and neonates, we measured the serum 25-hydroxyvitamin D (25OHD) levels in pregnant women, as well as measuring 25OHD levels in cord blood and breast milk. In pregnant women hospitalized for longer than 1 month, the serum 25OHD levels were decreased at delivery compared with those in control subjects (10.9 +/- 2.6 ng/l vs 19.5 +/- 4.9 ng/l; P0.01). Although the levels of 25OHD in the cord blood were not significantly different between the long-term hospitalized and control pregnant women in this study (9.36 +/- 1.7 ng/l vs 11.1 +/- 3.0 ng/l), the 25OHD concentrations in the cord blood were significantly lower than the maternal levels in both groups; the ratios of the levels in cord blood to sera in the long-term hospitalized women and control subjects were 82.1% and 60.3%, respectively. Long maternal hospitalization does not always cause neonatal vitamin D deficiency, but could be one of its major risk factors. Therefore, sufficient sunlight exposure and intake of sufficient vitamin D are considered to be important to prevent vitamin D deficiency in long-term hospitalized pregnant women as well as their babies. |
| Databáze: | OpenAIRE |
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