Predicting Short-Term Survival after Gross Total or Near Total Resection in Glioblastomas by Machine Learning-Based Radiomic Analysis of Preoperative MRI

Autor: Luis Jiménez-Roldán, Pedro Gonzalez, Ignacio Arrese, Rosario Sarabia, Daniel García-Pérez, Manuel Garcia-Galindo, Sergio García-García, Angel Perez-Nuñez, María Velasco-Casares, Tomás Zamora, Santiago Cepeda
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Cancers, Vol 13, Iss 5047, p 5047 (2021)
Cancers
Volume 13
Issue 20
ISSN: 2072-6694
Popis: Producción Científica
Radiomics, in combination with artificial intelligence, has emerged as a powerful tool for the development of predictive models in neuro-oncology. Our study aims to find an answer to a clinically relevant question: is there a radiomic profile that can identify glioblastoma (GBM) patients with short-term survival after complete tumor resection? A retrospective study of GBM patients who underwent surgery was conducted in two institutions between January 2019 and January 2020, along with cases from public databases. Cases with gross total or near total tumor resection were included. Preoperative structural multiparametric magnetic resonance imaging (mpMRI) sequences were pre-processed, and a total of 15,720 radiomic features were extracted. After feature reduction, machine learning-based classifiers were used to predict early mortality (
Databáze: OpenAIRE