Combined effect of heterogeneous target dose and heterogeneous radiosensitivity on tumor control probability for different fractionation regimens

Autor:	V Y, Kuperman, L M, Lubich, Gregory S, Spradlin
Rok vydání:	2022
Předmět:	Neoplasms Biophysics Humans General Physics and Astronomy Radiology Nuclear Medicine and imaging Dose Fractionation Radiation General Medicine Radiosurgery Radiation Tolerance Probability
Zdroj:	Physica Medica. 95:140-147
ISSN:	1120-1797
Popis:	To evaluate the combined effect of heterogeneous target dose and heterogeneous radiosensitivity on tumor control probability (TCP) for different number of fractions (NThe linear-quadratic (LQ) model is employed to study dependence of TCP on NFormula for the optimum target dose which maximizes TCP under the condition BEDIt is shown that the optimum mean dose in the target is defined by the standard deviations of the target dose (σ
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e005ab0a6da59971f424b4cfcb2fa62 https://doi.org/10.1016/j.ejmp.2021.12.003 Zobrazit plný text záznamu Full Text from ScienceDirect