Hepatic cryoablation: US monitoring of extent of necrosis in normal pig liver
| Autor: | Fred T. Lee, David M. Mahvi, Susan G. Chosy, Sharon M. Weber, Thomas F. Warner |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Pathology
medicine.medical_specialty Necrosis Swine business.industry medicine.medical_treatment Cryoablation Cryotherapy Cryosurgery Liver Maximum diameter Flow capacity medicine Animals Tissue necrosis Radiology Nuclear Medicine and imaging medicine.symptom Nuclear medicine business Pig liver Ultrasonography |
| Zdroj: | Radiology. 207:73-77 |
| ISSN: | 1527-1315 0033-8419 |
| DOI: | 10.1148/radiology.207.1.9530301 |
| Popis: | To determine the accuracy of ultrasonography (US) for prediction of hepatic tissue necrosis after cryoablation in normal pig liver.Five normal pig livers were treated with cryoablation monitored with US. After a single freeze cycle at 50% flow capacity, the widest diameter of the cryolesion was identified and marked with wire placement (22 wires in five lesions). Livers were removed 24 hours later, and wire tracks were marked with India ink. Livers were sectioned, and the distance was measured between wire tracks and tissue necrosis caused by freezing.The mean volume of areas of tissue necrosis was 11.6 cm3 +/- 4.0, the mean diameter was 2.9 cm +/- 1.0, and the mean maximum diameter was 2.9 cm +/- 0.7. The mean distance between the edge of necrosis and the wire track was 1.1 mm +/- 1.4. By excluding one outlier (6.5 mm), the mean distance from the ice ball to the necrotic area was 0.8 mm +/- 0.8. Uniform necrosis of hepatic parenchyma within the cryolesion was confirmed.US can be used to predict reliably the size of the necrotic area after hepatic cryoablation in normal pig liver. Knowledge of a small but consistent underestimation of tissue necrosis is important when planning cryoablation. |
| Databáze: | OpenAIRE |
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