Substrate-oriented selectivity in the Mg-mediated conjugate addition of bromoform to electron-deficient alkenes

Autor:	Irishi N. N. Namboothiri, Nishikant Satam, Saumyadip Nemu, Guddeangadi N. Gururaja
Rok vydání:	2020
Předmět:	chemistry.chemical_compound chemistry Organic Chemistry Substrate (chemistry) Electron Physical and Theoretical Chemistry Bromoform Selectivity Photochemistry Biochemistry Conjugate
Zdroj:	Organicbiomolecular chemistry. 18(29)
ISSN:	1477-0539
Popis:	The Mg-mediated conjugate addition of bromoform to a variety of electron-deficient alkenes has been investigated. In the case of nitrodienes and dibenzylideneacetones, tribromomethylated products were isolated, whereas spiro-cyclopropanated products were obtained with cyclic dibenzylideneketones and 3-olefinic oxindoles. The spiro-cyclopropyl ketones derived from cyclic dibenzylideneketones were successfully transformed into fused furans via the Cloke-Wilson rearrangement.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d968c6b1b844f3d2d35655008e809ed https://pubmed.ncbi.nlm.nih.gov/32663237 Zobrazit plný text záznamu