| Popis: |
As we have heard in the excellent review given by Dr. J . Couvreur , the occurrence of myocarditis and pericarditis caused by Coxsackie B viruses in infants, older children and adults is fairly well established and there does not seem to be much to be added. Nevertheless, I will take the opportunity to shortly mention a few such cases in connection with the epidemic of Coxsackie B 5 we have had the last years in Sweden. The cases reported here do not deviate much from those described previously (Table 1). However, there are certain points of interest the authors want to underline. In the actual cases there is a familial occurrence of Coxsackie virus infections which we have found so common for infections with enteroviruses. Thus, there are not less than four cases of pericarditis in one of the families, as you can see in Table 1. The pleomorphism in the c]inical picture is also striking. As in previous family studies the infection in the family of the five members seems to have been introduced by the youngest member of the family, the nine year old boy, the last to fall ill being the father. The isolation procedure for enteroviruses, in recent years in the State Bacteriological Laboratory, has been inoculation in monkey kidney tissue culture and in suckling mice. To a certain extent human embryonic lung and kidney has also been used. The results of attempted virus isolations from 2,028 specimens as far as Coxsackie B viruses are concerned are listed in Table 2. Of 61 Coxsackie B 5 viruses isolated almost all could be isolated in monkey kidney tissue culture, while 30 % could be isolated in suckling mice. Two percent was isolated only in suckling mice. About half of the positive specimens was also tested in human embryonic kidney |
