Continuous renal replacement therapy rescued life-threatening capillary leak syndrome in an extremely-low-birth-weight premature: a case report
| Autor: | Ya-Ting Li, Meng-Qi Duan, Ling-Ping Zhu, Zhuang-Gui Chen, Li-Fen Yang, Jia-Chang Ding, Li-Xia Li, Xin-Yi Tang |
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| Rok vydání: | 2020 |
| Předmět: |
Continuous renal replacement therapy
medicine.medical_treatment 030232 urology & nephrology Case Report Pediatrics RJ1-570 Hypoxemia Sepsis 03 medical and health sciences 0302 clinical medicine 030225 pediatrics medicine Humans Renal replacement therapy Hypoalbuminemia Premature Mechanical ventilation business.industry Infant Newborn medicine.disease Low birth weight Infant Extremely Low Birth Weight Anesthesia Anuria Female Capillary leak syndrome medicine.symptom business Infant Premature Capillary Leak Syndrome |
| Zdroj: | Italian Journal of Pediatrics Italian Journal of Pediatrics, Vol 47, Iss 1, Pp 1-4 (2021) |
| ISSN: | 1824-7288 |
| Popis: | Background Capillary leak syndrome (CLS) is a rare disease characterized by profound vascular leakage and presents as a classic triad of hypotension, hypoalbuminemia and hemoconcentration. Severe CLS is mostly induced by sepsis and generally life-threatening in newborns, especially in premature infants. Continuous renal replacement therapy (CRRT) plays an important role of supportive treatment for severe CLS. Unfortunately, CRRT in preterm infants has rarely been well defined. Case presentation We report the case of a 11-day-old girl with CLS caused by sepsis, who was delivered by spontaneous vaginal delivery (SVD) at gestational age of 25 weeks and 4 days, and a birth weight of 0.89 Kilograms(kg). The infant received powerful management consisting of united antibiotics, mechanical ventilation, intravenous albumin and hydroxyethyl starch infusion, vasoactive agents, small doses of glucocorticoids and other supportive treatments. However, the condition rapidly worsened with systemic edema, hypotension, pulmonary exudation, hypoxemia and anuria in about 40 h. Finally, we made great efforts to perform CRRT for her. Fortunately, the condition improved after 82 h’ CRRT, and the newborn was rescued and gradually recovered. Conclusion CRRT is an effective rescue therapeutic option for severe CLS and can be successfully applied even in extremely-low-birth-weight premature. |
| Databáze: | OpenAIRE |
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