Is IFN expression by NK cells a hallmark of severe COVID-19?

Autor: Bárbara Guimarães Csordas, Pedro Henrique de Sousa Palmeira, Rephany Fonseca Peixoto, Fernando Cézar Queiroz Davis dos Santos Comberlang, Isac Almeida de Medeiros, Fátimade Lourdes Assunção Araújo de Azevedo, Robson Cavalcante Veras, Daniele Idalino Janebro, Ian P.G. Amaral, José Maria Barbosa-Filho, Tatjana Souza Lima Keesen
Rok vydání: 2022
Předmět:
Zdroj: Cytokine. 157:155971
ISSN: 1043-4666
DOI: 10.1016/j.cyto.2022.155971
Popis: Natural Killer cells (NK) are crucial in host defense against viruses. There are many unanswered questions about the immune system in COVID-19, especially the mechanisms that contribute to the development of mild or severe forms of the disease. Although NK cells may have an essential role in the pathogenesis of COVID-19, the mechanisms involved in this process are not yet fully elucidated. Here, we demonstrate that CD3
Databáze: OpenAIRE
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