HIV incidence and compliance with deferral criteria over three progressively shorter time deferrals for men who have sex with men in Canada
| Autor: | Wenli Fan, Qi-Long Yi, Lori Osmond, Niamh Caffrey, Mindy Goldman, Sheila F. O'Brien |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
Canada Immunology Human immunodeficiency virus (HIV) Blood Donors HIV Infections medicine.disease_cause Men who have sex with men Sexual and Gender Minorities immune system diseases Humans Immunology and Allergy Medicine Homosexuality Male Deferral reproductive and urinary physiology business.industry Incidence Incidence (epidemiology) Hiv incidence virus diseases Hematology Residual risk Blood donor business Demography |
| Zdroj: | Transfusion. 62:125-134 |
| ISSN: | 1537-2995 0041-1132 |
| DOI: | 10.1111/trf.16753 |
| Popis: | BACKGROUND In Canada, the deferral for men who have sex with men (MSM) has been progressively reduced from a permanent deferral for MSM since 1977, to 5 years, 1 year, and, most recently, 3 months. We estimated human immunodeficiency virus (HIV) residual risk and compliance with the MSM time deferral after each change. METHODS Four anonymous online compliance surveys were carried out before and after each change. HIV incidence and prevalence were monitored from 2010 to 2021. Residual risk was estimated using the incidence-window period model. RESULTS Human immunodeficiency virus prevalence, incidence, and residual risk did not change with incrementally shorter MSM deferrals. The residual risk per million donations post 3-month deferral was 0.05 (0.001-0.371). Men with temporally remote MSM history became eligible and, therefore, compliant as the deferral periods decreased (Cochran-Armitage p value = |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text