Post-traumatic stress burden in a sample of hospitalized patients with Bipolar Disorder: Which impact on clinical correlates and suicidal risk?
| Autor: | Liliana Dell'Osso, Claudia Carmassi, Elisa Diadema, Annalisa Cordone, Valerio Dell'Oste, Claudia Foghi, Carlo Antonio Bertelloni, Virginia Pedrinelli |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Hospitals Psychiatric Male Substance abuse medicine.medical_specialty Bipolar Disorder Substance-Related Disorders Cross-sectional study Alcohol abuse Poison control Comorbidity Trauma behavioral disciplines and activities DSM-5 Suicidal Ideation Stress Disorders Post-Traumatic Young Adult 03 medical and health sciences 0302 clinical medicine Risk Factors mental disorders Humans Medicine Bipolar disorder Psychiatry Psychotic MOODS-SR PTSD Suicide Inpatients business.industry Traumatic stress Middle Aged medicine.disease 030227 psychiatry Alcoholism Psychiatry and Mental health Clinical Psychology Cross-Sectional Studies Mood Italy Quality of Life Female business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Affective Disorders. 262:267-272 |
| ISSN: | 0165-0327 |
| DOI: | 10.1016/j.jad.2019.10.044 |
| Popis: | Background Increasing evidence suggests Bipolar Disorder (BD) to be frequently associated to a history of traumatic experiences and Post-traumatic Stress Disorder (PTSD), with consequent greater symptoms severity, number of hospitalizations and worsening in quality of life. The aim of the present study was to investigate the lifetime exposure to traumatic events and PTSD rates in-patients with BD and to analyze the relationships between PTSD symptoms, clinical characteristics and severity of the mood disorder. Methods A consecutive sample of 212 in-patients with a DSM-5 diagnosis of BD was enrolled at the psychiatric unit of a major University hospital in Italy and assessed by the SCID-5 and MOOD Spectrum-Self Report lifetime version (MOODS-SR). Socio-demographic characteristics, clinical features, substance or alcohol abuse, history of suicide related behaviors were also collected. Results Lifetime trauma exposure emerged in 72.3% subjects, with a DSM-5 PTSD diagnosis reported by 35.6%. Patients with PTSD showed more frequently a (hypo)manic episode at onset, alcohol or substance abuse, psychotic features, suicide behaviors, higher scores in almost all the MOODS-SR domains, compared to those without PTSD. Limitations Cross sectional study. Lack of data about the time since trauma exposure or PTSD onset. Conclusions Our findings show a history of multiple traumatic experiences in hospitalized patients with BD besides high rates of PTSD, with the co-occurrence of these conditions appearing to be related to a more severe BD. Detailed investigation of post-traumatic stress symptoms is recommended for the relevant implications on the choice of a tailored treatment and the prognosis assessment. |
| Databáze: | OpenAIRE |
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