COVID-PIRO (Predisposition, Insult, Response, Organ Dysfunction) Score: A Reliable Predictor of Outcomes in COVID-19 Patients Admitted in Intensive Care Unit
| Autor: | Dhruv Talwar, Sanyukta Hepat, Jahnabi Bhagawati, Sunil Kumar, Divit Shah, Praraj Jaiswal, Sameera Dronamraju, Sourya Acharya, Irhsad Vs, Vidyashree Hulkoti |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
rural hospital Pulmonology Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Infectious Disease intensive care unit law.invention Sepsis law Internal medicine Internal Medicine piro score Medicine business.industry Mortality rate Organ dysfunction General Engineering medicine.disease Intensive care unit Pneumonia covid-19 outcome Observational study medicine.symptom business |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Introduction To measure the severity of sepsis and pneumonia in adult patients with coronavirus disease 2019 (COVID-19), the PIRO model (predisposition, insult, response, organ dysfunction) was adopted as a scoring system. In this study, the PIRO model was modified to classify the severity of pneumonia in adults and predict mortality risk infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), admitted to a tertiary intensive care unit (ICU) in central rural India. Method This prospective, observational study was conducted in the Department of Medicine, in rural medical college at Wardha, Maharashtra, India from May 2020 to May 2021. Patients with reverse transcription-polymerase chain reaction (RT-PCR) positive for COVID-19 and whose age was more than 18 years admitted in the intensive care unit were included in the study. Results A total of 240 patients were included in the analysis having mean age of 60.27 ± 15.3 years. Number of deaths were 115 out of 240 (48.3%). Mean ICU stay was 9.09 ± 6.34 days. PIRO score ≤14.5 had a mortality rate of 1.25% as compared to the group having PIRO>14.5 which had mortality of 27.5%, with a cure rate of 26.25% and 5% respectively in both groups (p = 0.0001). Conclusion COVID-PIRO modified PIRO score was a highly sensitive and specific model in predicting in-hospital mortality but it is moderately sensitive in predicting ICU stay. |
| Databáze: | OpenAIRE |
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