The role of routine fine-needle aspiration in the diagnosis of infected necrotizing pancreatitis
| Autor: | Mark C, van Baal, Thomas L, Bollen, Olaf J, Bakker, Harry, van Goor, Marja A, Boermeester, Cees H, Dejong, Hein G, Gooszen, Erwin, van der Harst, Casper H, van Eijck, Hjalmar C, van Santvoort, Marc G, Besselink, M A, Questa |
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| Přispěvatelé: | AII - Amsterdam institute for Infection and Immunity, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Surgery, CCA -Cancer Center Amsterdam, RS: NUTRIM - R2 - Gut-liver homeostasis |
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Databases Factual Biopsy Fine-Needle MULTICENTER GUIDELINES CLASSIFICATION PROPHYLAXIS Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] Interquartile range Preoperative Care Post-hoc analysis Biopsy MANAGEMENT medicine Humans In patient Pancreas Aged Retrospective Studies COMPLICATIONS medicine.diagnostic_test Pancreatitis Acute Necrotizing business.industry DEBRIDEMENT Retrospective cohort study Middle Aged SURGICAL INTERVENTION NECROSECTOMY medicine.disease Surgery Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10] body regions Treatment Outcome Fine-needle aspiration Drainage Pancreatitis Female TRIAL Radiology Tomography X-Ray Computed business Necrotizing pancreatitis |
| Zdroj: | Surgery, 155, 3, pp. 442-8 Surgery, 155, 442-8 Surgery, 155(3), 442-448. Mosby Inc. Surgery, 155(3), 442-448. MOSBY-ELSEVIER |
| ISSN: | 0039-6060 |
| Popis: | Item does not contain fulltext BACKGROUND: Diagnosing infected necrotizing pancreatitis (INP) may be challenging. The aim of this study was to determine the added value of routine fine-needle aspiration (FNA) in addition to clinical and imaging signs of infection in patients who underwent intervention for suspected INP. METHODS: We conducted a post hoc analysis of 208 consecutive patients from a prospective, multicenter database who underwent intervention because of suspected INP. In retrospect, 3 groups were constructed based on the patients preoperative characteristics: Clinical, imaging, and FNA. Patients in the clinical group had clinical signs of infection but no gas on preoperative computed tomography (CT) and no FNA performed before intervention. Patients in the imaging group had gas bubbles on the preoperative CT but no was FNA performed, whereas patients in the FNA group had a positive FNA before intervention. The reference standard for infection was the culture taken during the first intervention (either catheter drainage or necrosectomy). RESULTS: The initial intervention for INP was performed a median of 27 days (interquartile range, 20-39) after admission without difference between the 3 groups (P = .15). Infection was confirmed in 80% of 92 patients of the clinical group, in 94% of 88 patients of the imaging group, and in 86% of 28 patients of the FNA group (P = .07). Mortality was 19% and was not different between groups (P = .39). CONCLUSION: INP can generally be diagnosed based on clinical or imaging signs of infection. FNA may be useful in patients with unclear clinical signs and no imaging signs of INP. |
| Databáze: | OpenAIRE |
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