Ambient temperature and infarct size, microvascular obstruction, left ventricular function and clinical outcomes after ST-segment elevation myocardial infarction
| Autor: | Zixuan Zhang, Flavien Vincent, Manesh R. Patel, Akiko Maehara, E. Magnus Ohman, Shmuel Chen, Ingo Eitel, Holger Thiele, Gregg W. Stone, Matheus Simonato, Ori Ben-Yehuda, Bjorn Redfors |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Myocardial Infarction Ventricular Function Left law.invention Randomized controlled trial law Internal medicine medicine Humans ST segment cardiovascular diseases Myocardial infarction Aged Ejection fraction business.industry Microcirculation Incidence (epidemiology) Temperature Percutaneous coronary intervention General Medicine Middle Aged Prognosis medicine.disease Treatment Outcome Heart failure Conventional PCI Cardiology ST Elevation Myocardial Infarction Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Coronary Artery Disease. 33:81-90 |
| ISSN: | 0954-6928 |
| DOI: | 10.1097/mca.0000000000001099 |
| Popis: | OBJECTIVES Incidence and prognosis of ST-segment elevation myocardial infarction (STEMI) vary according to ambient temperature and season. We sought to assess whether season and temperature on the day of STEMI are associated with infarct size, microvascular obstruction (MVO), left ventricular ejection fraction (LVEF) and clinical outcomes after primary percutaneous coronary intervention (PCI). METHODS Individual patient data from 1598 patients undergoing primary PCI in six randomized clinical trials were pooled. Infarct size was evaluated by cardiac magnetic resonance within 30 days in all trials. Patients were categorized either by whether they presented on a day of temperature extremes (minimum temperature 25 °C) or according to season. RESULTS A total of 558/1598 (34.9%) patients presented with STEMI on a day of temperature extremes, and 395 (24.7%), 374 (23.4%), 481 (30.1%) and 348 (21.8%) presented in the spring, summer, fall and winter. After multivariable adjustment, temperature extremes were independently associated with larger infarct size (adjusted difference 2.8%; 95% CI, 1.3-4.3; P |
| Databáze: | OpenAIRE |
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