Neuralgic amyotrophy triggered by hepatitis E virus: a particular phenotype

Autor: François Cassim, Quentin Scanvion, Aurélia Lanteri, Thierry Perez, Pierre-Yves Hatron, Marc Lambert, Olivier Outteryck, Sandrine Morell-Dubois
Přispěvatelé: Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Université de Lille, None
Rok vydání: 2017
Předmět:
Zdroj: Journal of Neurology
Journal of Neurology, 2017, 264 (4), pp.770-780. ⟨10.1007/s00415-017-8433-z⟩
Journal of Neurology, Springer Verlag, 2017, 264 (4), pp.770-780. ⟨10.1007/s00415-017-8433-z⟩
ISSN: 1432-1459
0340-5354
DOI: 10.1007/s00415-017-8433-z
Popis: International audience; Objective: The neuralgic amyotrophy may be of difficult diagnosis, due to phenotypic variability, with different initial presentations (upper plexus multiple mononeuropathy, lumbosacral involvement, distal reached, phrenic involvement). To date, there is little guidance on these patients’ therapeutic management, especially those for which neuralgic amyotrophy is triggered by hepatitis E virus (HEV-NA). The study aims to identify specific features that characterize patients bearing the neuralgic amyotrophy triggered by HEV. Methods: We first describe a new case report of HEV-neuralgic amyotrophy, with delayed diaphragmatic reach. Then, the literature was searched for reports of HEV-NA (n=39), and neuralgic amyotrophy with phrenic paresis (n=42) from 1999 to June 2016. Relevant data were retrieved, analyzed and compared with the parameters of idiopathic neuralgic amyotrophy (n=199) of the largest cohort, described by Van Alfen and Van Engelen in 2006. Results: Compared to the published cohort, HEV-NA patients were more likely to be men (M/F 34/5 versus 136/ 63, p=0.017), with more frequent bilateral symptoms (86.8% cases versus 28.5%, p
Databáze: OpenAIRE