Oculopharyngeal dystrophy: Ultrastructure of muscles distant from the primary myopathy
| Autor: | F. J. Wilson, J. W. Kozachek |
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| Rok vydání: | 1982 |
| Předmět: |
Male
Autopsy Biology Sarcomere Muscular Dystrophies Pathology and Forensic Medicine Psoas Muscles Oculopharyngeal muscular dystrophy Cellular and Molecular Neuroscience Myofibrils medicine Humans Myopathy Aged Muscles Anatomy medicine.disease Microscopy Electron Oculomotor Muscles Ultrastructure Pharynx Neurology (clinical) medicine.symptom Myofibril Oculopharyngeal dystrophy |
| Zdroj: | Acta Neuropathologica. 57:7-12 |
| ISSN: | 1432-0533 0001-6322 |
| DOI: | 10.1007/bf00688872 |
| Popis: | The pectoral and psoas muscles from a 72-year-old man afflicted with oculopharyngeal muscular dystrophy were processed at autopsy for electron microscopy. The ultrastructural analyses of the pectoral muscle showed myofibrils which exhibited Z line streaming and a general breakdown in the organization of the sarcomere. In addition, some of the myofibrils displayed sites of degeneration at the center of the A band. The changes in the psoas muscles which are distant from the primary myopathic loci of oculopharyngeal muscular dystrophy were more extensive than that seen in the pectoral muscle. Control tissues showed intact myofibrils and little postmortem alteration. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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