Biodegradable Magnetic Molecularly Imprinted Anticancer Drug Carrier for the Targeted Delivery of Docetaxel

Autor: Zeeshan Ali, Muhammad Sajid, Suryyia Manzoor, Muhammad Mahboob Ahmad, Muhammad Imran Khan, Noureddine Elboughdiri, Muhammad Kashif, Abdallah Shanableh, Wajdi Rajhi, Wael Mersni, Emin Bayraktar, Sahbi Ben Salem
Rok vydání: 2022
Předmět:
Zdroj: ACS Omega. 7:28516-28524
ISSN: 2470-1343
DOI: 10.1021/acsomega.2c03299
Popis: Molecularly imprinted biodegradable polymers are receiving considerable attention in drug delivery due to their ability of targeted recognition and biocompatibility. This study reports the synthesis of a novel fluorescence-active magnetic molecularly imprinted drug carrier (MIDC) using a glucose-based biodegradable cross-linking agent for the delivery of anticancer drug docetaxel. The magnetic molecularly imprinted polymer (MMIP) was characterized through scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction spectroscopy, and vibrating sample magnetometry (VSM). The MMIP presented a magnetization value of 0.0059 emu g
Databáze: OpenAIRE