A randomized, evaluator-blinded, controlled study of the effectiveness and safety of small gel particle hyaluronic acid for lip augmentation
| Autor: | Xiaoming Lin, Ava Shamban, Lisa Donofrio, Robert A Axford-Gatley, David Bank, Fredric S Brandt, Jeffrey S. Dover, Mark S Nestor, Michael J. Theisen, Sue Ellen Cox, Stacy R. Smith, Robert Weiss, Ira Lawrence, Daniel Stewart, Richard G. Glogau, Steven Grekin |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Lower lip Dermatology chemistry.chemical_compound Young Adult Hyaluronic acid medicine Humans Single-Blind Method Hyaluronic Acid Particle Size Adverse effect Aged Lip augmentation business.industry Upper lip General Medicine Middle Aged Lip Surgery stomatognathic diseases chemistry Female business After treatment |
| Zdroj: | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 38(7 Pt 2) |
| ISSN: | 1524-4725 |
| Popis: | Objectives To assess the effectiveness and safety of small gel particle hyaluronic acid (SGP-HA) for lip augmentation. Methods Adults (n = 180; aged 18–65) scoring 1 (very thin) to 2 (thin) on the 5-point validated Medicis Lip Fullness Scale (MLFS) for the upper or lower lip were randomized (3:1) to SGP-HA (≤1.5 mL/lip) or no treatment. Co-primary effectiveness end points were blinded-evaluator MLFS score for upper or lower lip at week 8. Secondary end points (MLFS score, independent photographic review, Global Aesthetic Improvement Scale [GAIS], safety assessments) were measured throughout the study. Results Statistically significantly more MLFS responders (≥1 grades of MLFS improvement at week 8) received SGP-HA (93% combined upper and lower lip responders [95% upper lip; 94% lower lip]) than no treatment (29% combined; p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text