Type of axial analgesia does not influence time to vaginal delivery in a Proportional Hazards Model

Autor: Faustino R. Pérez-López, Javier Haya, Silvia Gil Trujillo, Javier Pascual-Ramírez
Rok vydání: 2012
Předmět:
Zdroj: Archives of Gynecology and Obstetrics. 286:873-880
ISSN: 1432-0711
0932-0067
DOI: 10.1007/s00404-012-2360-0
Popis: To create a Proportional Hazards Model of prospective factors associated with time-to-vaginal-delivery (TTVD). We analyzed a group of 144 women undergoing childbirth who received one out of two possible axial analgesia techniques, to find-out factors associated with TTVD. The patients were randomly assigned to receive either a levobupivacaine labor epidural (bolus concentration 0.25 % or less; infusion concentration 0.125 % or less) or a combined spinal–epidural procedure (morphine 0.20 mg, fentanyl 25 µg and hyperbaric bupivacaine 2.5 mg as spinal components) for labor analgesia. The factors initially chosen were: mother age, height and weight, parity, gestational age, newborn weight, type of labor, analgesic procedure, levobupivacaine and fentanyl doses, Bromage scale, pain Numeric Rating Scale, and a satisfaction interview. Cesarean section was the censored variable in our model. A systematic multivariate Cox regression was performed. Our Final Model stated that nulliparous women had 2.5 times more chances of having longer TTVD than primiparous (p
Databáze: OpenAIRE