Validation of overactive bladder questionnaire (1-week recall version) in medically complex elderly patients with overactive bladder
| Autor: | Andreas M. Pleil, Sheila Quinn, Martin Carlsson, Joseph C. Cappelleri, Andrew G. Bushmakin, Alexandra I. Barsdorf |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Psychometrics Urology 030232 urology & nephrology urologic and male genital diseases Statistics Nonparametric 03 medical and health sciences 0302 clinical medicine Surveys and Questionnaires Humans Medicine Patient Reported Outcome Measures Benzhydryl Compounds Aged Aged 80 and over Recall Urinary Bladder Overactive business.industry Reproducibility of Results Obstetrics and Gynecology medicine.disease humanities female genital diseases and pregnancy complications Treatment Outcome Overactive bladder 030220 oncology & carcinogenesis Quality of Life Physical therapy Urological Agents Female Factor Analysis Statistical business |
| Zdroj: | International Urogynecology Journal. 28:1857-1863 |
| ISSN: | 1433-3023 0937-3462 |
| Popis: | The 33-item Overactive Bladder questionnaire (OAB-q; 1-week recall version) has been psychometrically validated in middle-aged, generally healthy patients with overactive bladder. The present analysis was conducted to determine the psychometric validity of the OAB-q in medically complex elderly patients.OAB-q structure was evaluated using a second-order confirmatory factor analysis (CFA) model with five domains and one aggregated domain, using pooled data from two clinical trials (786 observations) for urgency urinary incontinence (UUI). Psychometric validity was evaluated with CFA, Cronbach coefficient α (CCA) for reliability, Spearman correlations for convergent validity, differences in OAB-q scores in relation to UUI severity and Patient Perception of Bladder Condition (PPBC) scores for known-groups validity, and effect size (ES) of differences in mean scores of OAB-q domains over time for treatment responsiveness.Participants were predominantly female (82.2%) and white (85.9%); mean age was 75.0 years. The second-order CFA was confirmed with a Bentler's comparative fit index of 0.90, t values for path coefficients of1.96, and standardized path coefficients of0.40. OAB-q domains demonstrated good internal consistency (CCA0.7). Convergent validity was supported by moderate correlations (0.4-0.7) between OAB-q domain and PPBC scores. Significant differences in OAB-q domain scores between groups with different symptom severity established known-groups validity. Significant changes in mean OAB-q scores from baseline to week 12 with moderate-to-large ES (0.50-0.80) demonstrated treatment responsiveness.The OAB-q demonstrates reliability, concurrent and discriminant validity, and responsiveness to treatment. The evidence shows that the OAB-q is psychometrically sound for use in medically complex elderly patients with overactive bladder. |
| Databáze: | OpenAIRE |
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