Ocular Complications of Cryptococcal Meningitis in Patients with HIV
| Autor: | Heather M. Walls, Joan Duggan |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Antifungal Agents genetic structures Immunology Cryptococcus Human immunodeficiency virus (HIV) Flucytosine Dermatology Meningitis Cryptococcal Blindness medicine.disease_cause Amphotericin B medicine Humans In patient Intracranial pressure AIDS-Related Opportunistic Infections biology business.industry biology.organism_classification medicine.disease eye diseases Optimal management Surgery Infectious Diseases Female business Cryptococcal meningitis Meningitis |
| Zdroj: | Journal of the International Association of Physicians in AIDS Care. 11:283-288 |
| ISSN: | 1545-1097 |
| DOI: | 10.1177/1545109712448537 |
| Popis: | AIDS-related cryptococcal meningitis can result in significant vision loss, but the risk factors, prognostic features, and optimal management of patients with ocular complications is unknown. We present 2 cases of blindness associated with cryptococcal meningitis and review the literature for associated cases. Twenty-six additional cases of vision deterioration or loss as a result of HIV-associated cryptococcal meningitis were reviewed. Irreversible and complete loss of vision occurred in 14 patients (50%). Permanent vision loss was more likely to occur in patients with ocular symptoms and neurologic signs at presentation. Nearly all patients with permanent visual loss experienced blindness within the first week after hospital admission. Visual complications are not uncommon in cryptococcal meningitis, and once vision loss occurs, it is often irreversible regardless of control of infection or intracranial pressure. Visual complaints in cryptococcal meningitis should be considered a potentially poor prognostic sign. |
| Databáze: | OpenAIRE |
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