Effect of 5-Line Signs in the Prediction of Staging, Progression, and Prognosis of Peripheral Lung Carcinoma
| Autor: | Qun Li, Yuefu Zhan, Jinlong He, Anle Yu |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Lung Neoplasms Sensitivity and Specificity 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine Carcinoma Humans Radiology Nuclear Medicine and imaging Multislice Lung cancer Lung Survival rate Aged Neoplasm Staging Aged 80 and over business.industry Middle Aged Prognosis medicine.disease Spiral computed tomography Peripheral Survival Rate medicine.anatomical_structure Tumor progression Disease Progression Radiographic Image Interpretation Computer-Assisted Female Radiology business Tomography Spiral Computed 030217 neurology & neurosurgery |
| Zdroj: | Journal of Computer Assisted Tomography. 44:295-304 |
| ISSN: | 0363-8715 |
| DOI: | 10.1097/rct.0000000000000941 |
| Popis: | BACKGROUND The single line of the normal interlobar fissure shown on a thin section image can be reconstructed as a 5-line sign on axial maximal intensity projection. The line between the lung nodule and the pleura is called the pleural tail sign on thin image. On the axial maximal intensity projection, it can also be reconstructed as the 5-line sign or fewer than 5 lines. OBJECTIVE This study aimed to observe the effect of 5-line signs in staging, progression, and prognosis of peripheral lung carcinoma. MATERIALS AND METHODS This study included 132 patients with peripheral lung carcinoma. Among these patients, 93 were men and 39 were women, with an age range of 27 to 82 years and a lung nodule range of 0.98 to 8.75 cm. Maximal intensity projection was reconstructed based on 1.0 or 1.25 mm of thin-slice images in multislice spiral computed tomography. Five-line signs on the margin of the nodule (mass) were observed and were classified into grades 1 to 4 according to the sharpness of the 5-line signs. RESULTS Multivariate logistic regression analysis showed that the sharpness of the 5-line signs was correlated with N and TNM staging of peripheral lung carcinoma (P = 0.012, P = 0.016). The lower the sharpness of the 5-line signs, the greater the number of cases of progression of the tumor (P < 0.001), and thus the higher the mortality rate and the lower the survival rate (P = 0.001). The sensitivity and specificity of predicting tumor progression were 56.3% and 93.3%, and those of tumor prognosis were 61.1% and 82.4%, respectively. CONCLUSIONS The sharpness of the 5-line signs has certain effects on the prediction of invasion, progression, and prognosis of lung carcinoma, particularly of small lung cancer (≤3.0 cm). |
| Databáze: | OpenAIRE |
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