Physiologic Course of Female Reproductive Function: A Molecular Look into the Prologue of Life
| Autor: | Mervin Chávez-Castillo, Valmore Bermúdez, Milagros Rojas, Luis Carlos Olivar, Jessenia Morillo, Joselyn Rojas, José Mejías, María Calvo |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Ovulation
medicine.medical_specialty Offspring media_common.quotation_subject Physiology Mitosis Ovary Fertility Review Article Biology lcsh:Gynecology and obstetrics Oogenesis Internal medicine Follicular phase medicine Humans Gonadal Steroid Hormones Menstrual cycle lcsh:RG1-991 Menstrual Cycle media_common Ovum Embryonic Induction Pregnancy Cell Death Reproduction Puberty Obstetrics and Gynecology medicine.disease Neurosecretory Systems Prenatal development Meiosis Endocrinology medicine.anatomical_structure Androgens Female |
| Zdroj: | Journal of Pregnancy Journal of Pregnancy, Vol 2015 (2015) |
| ISSN: | 2090-2735 2090-2727 |
| Popis: | The genetic, endocrine, and metabolic mechanisms underlying female reproduction are numerous and sophisticated, displaying complex functional evolution throughout a woman’s lifetime. This vital course may be systematized in three subsequent stages: prenatal development of ovaries and germ cells up untilin uteroarrest of follicular growth and the ensuing interim suspension of gonadal function; onset of reproductive maturity through puberty, with reinitiation of both gonadal and adrenal activity; and adult functionality of the ovarian cycle which permits ovulation, a key event in female fertility, and dictates concurrent modifications in the endometrium and other ovarian hormone-sensitive tissues. Indeed, the ultimate goal of this physiologic progression is to achieve ovulation and offer an adequate environment for the installation of gestation, the consummation of female fertility. Strict regulation of these processes is important, as disruptions at any point in this evolution may equate a myriad of endocrine-metabolic disturbances for women and adverse consequences on offspring both during pregnancy and postpartum. This review offers a summary of pivotal aspects concerning the physiologic course of female reproductive function. |
| Databáze: | OpenAIRE |
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