Successful Management of Severe Bromethalin Toxicosis in a Dog
| Autor: | Lori S. Waddell, Robert H. Poppenga, Vincent J. Thawley, Bridget M. Lyons |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
0106 biological sciences Intravenous lipid emulsion Poison control Pharmacology 01 natural sciences chemistry.chemical_compound Dogs Animals Medicine Ingestion Mannitol Rodenticide Dog Diseases Small Animals Aniline Compounds Plant Extracts business.industry Poisoning 010401 analytical chemistry Ginkgo biloba Rodenticides Pesticide Bromethalin Diuretics Osmotic 0104 chemical sciences chemistry business 010606 plant biology & botany |
| Zdroj: | Journal of the American Animal Hospital Association. 55 |
| ISSN: | 1547-3317 0587-2871 |
| Popis: | The use of bromethalin rodenticides has risen since 2011, and in some states, it is the most common rodenticide ingestion reported to poison control. Although intravenous lipid emulsion (ILE) has been previously reported to lower serum desmethylbromethalin levels in an asymptomatic dog, and repeated mannitol has been investigated in a laboratory setting, there are no published reports of successful treatment of symptomatic bromethalin toxicosis in dogs. A 9 yr old castrated male Norwich terrier was evaluated for obtunded mentation, seizures, cranial nerve deficits, and tetraparesis secondary to bromethalin toxicosis. The patient was treated with ILE, mannitol, and ginkgo biloba and returned to normal neurological function. Bromethalin exposure was confirmed by serum desmethylbromethalin levels. Previous literature indicates that the prognosis for patients who suffer from symptomatic bromethalin toxicosis is poor to grave, and the return to normal neurological function after severe toxicosis has not been reported. ILE, mannitol, and ginkgo biloba are readily available and relatively inexpensive, and in combination may be of benefit in symptomatic bromethalin intoxication. |
| Databáze: | OpenAIRE |
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