Are Coronary Artery Anomalies an Accelerating Factor for Coronary Atherosclerosis Development?

Autor: Gianfranco Franco, Daniele Rossi, Alberto Zamboni, Marzio Gemelli, Gianluca Rigatelli, Mirella Grazio, Giorgio Rigatelli, Giorgio Docali, Paolo Rossi
Rok vydání: 2004
Předmět:
Zdroj: Angiology. 55:29-35
ISSN: 1940-1574
0003-3197
DOI: 10.1177/000331970405500105
Popis: The relevance of benign congenital coronary anomalies (CAAs) in the atherosclerotic process is still confused despite the number of single reports of coronary artery disease in CAAs. The present study is aimed at assessing the role of CAAs on the progression of coronary artery disease (CAD). A review of the last 15,000 coronary angiographies was performed to select patients with CAAs, and they were divided into 2 groups on the basis of the presence (group I) or the absence (group II) of CAD. Clinical and instrumental records of the selected patients were reviewed and the numbers of cardiovascular events for each group (acute myocardial infarct, unstable angina, silent ischemia, bypass or percutaneous transluminal coronary angio plasty (PTCA) interventions, and cardiovascular death) were recorded from the date of diagnosis to July 2002. Group I (22 patients, mean age 64.1 ±9.1 years, F/M = 10/12) and group II (17 patients, mean age 66.5 ± 10.6 years, F/M = 7/10) were similar for age and ejection fraction values. The presence of risk factors was statistically higher in group I. The number of patients with cardiovascular events was significantly higher in group I: 50% (11 patients) in group I vs 12% (2 patients) in group II, p
Databáze: OpenAIRE