Antimicrobial and antileishmanial xanthones from the stem bark ofAllanblackia gabonensis(Guttiferae)
| Autor: | Juliette Catherine Vardamides, Michèle Meyer, Anatole Guy Blaise Azebaze, Alexis Valentin, Veronique P. Beng, A. E. Nkengfack, L. Acebey, B. M. W. Ouahouo, Victor Kuete |
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| Rok vydání: | 2008 |
| Předmět: |
Antifungal Agents
Allanblackia gabonensis Campesterol Gram-positive bacteria Antiprotozoal Agents Microbial Sensitivity Tests Plant Science Biochemistry Analytical Chemistry chemistry.chemical_compound Clusiaceae Xanthone Plant Bark Animals Leishmania Bacteria Molecular Structure Plant Stems biology Traditional medicine Organic Chemistry biology.organism_classification Antimicrobial Anti-Bacterial Agents chemistry Phytochemical |
| Zdroj: | Natural Product Research. 22:333-341 |
| ISSN: | 1478-6427 1478-6419 |
| Popis: | The phytochemical study of stem bark of Allanblackia gabonensis has resulted in the isolation and characterisation of one new xanthone derivative, named allanxanthone D, together with 10 known compounds, including 6 xanthones derivatives, allanxanthone A, 1,5-dihydroxyxanthone, 1,7-dihydroxyxanthone and 1,3,6,7-tetrahydroxy-2-(3-methylbut-2-enyl)xanthone, forbexanthone, 6-deoxyisojacareubin, one polyisoprenylated benzophenone, guttiferone F, one flavanol, epicathechin, two phytosterols, beta-sitosterol and campesterol. The structures of these compounds were established on the basis of one- and two-dimensional NMR homo- and hetero-nuclear evidence. These compounds were evaluated for their activity against Leishmania amazonensis in vitro and antimicrobial activities against a range of Gram negative and Gram positive bacteria. |
| Databáze: | OpenAIRE |
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