Towards a better QALY model

Autor:	Jose Luis Pinto-Prades, Xabier Badía-Llach, Ildefonso Méndez-Martínez, Jose-Maria Abellan-Perpiñan
Rok vydání:	2006
Předmět:	Predictive validity Cost–utility analysis Models Statistical Health Status Health Policy Reproducibility of Results Time tradeoff Exponential models Health Surveys Health states Power coefficient Spain Econometrics Economics Humans Quality-Adjusted Life Years
Zdroj:	Health Economics. 15:665-676
ISSN:	1099-1050 1057-9230
DOI:	10.1002/hec.1095
Popis:	Summary This paper presents a test of the predictive validity of various classes of QALY models (i.e. linear, power and exponential models). We first estimated TTO utilities for 43 EQ-5D chronic health states and next these states were embedded in nonchronic health profiles. The chronic TTO utilities were then used to predict the responses to TTO questions with nonchronic health profiles. We find that the power QALY model clearly outperforms linear and exponential QALY models. Optimal power coefficient is 0.65. Our results suggest that TTO-based QALY calculations may be biased. This bias can be corrected using a power QALY model. Copyright # 2006 John Wiley & Sons, Ltd.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994d6abffc196a8624e66ad87751d265 https://doi.org/10.1002/hec.1095 Zobrazit plný text záznamu Plný text