Recent Advances in Organocatalyzed Asymmetric sulfa‐Michael Addition Triggered Cascade Reactions
Autor: | Cheng Niu, Da‐Ming Du |
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Rok vydání: | 2023 |
Předmět: | |
Zdroj: | The Chemical Record. |
ISSN: | 1528-0691 1527-8999 |
DOI: | 10.1002/tcr.202200258 |
Popis: | The sulfa-Michael addition reaction is a crucial subset of the Michael addition reaction, and aroused the interest of numerous synthetic biologists and chemists. In particular, sulfa-Michael addition triggered cascade reaction has developed quickly in recent years because it offers an efficient method to construct C-S bonds and other bonds in one approach, which is widely applicable for building chiral pharmaceuticals, their intermediates, and natural compounds. This review emphasizes the recent advancements in sulfa-Michael addition-triggered cascade reactions for the stereoselective synthesis of sulfur-containing compounds, including sulfa-Michael/aldol, sulfa-Michael/Henry, sulfa-Michael/Michael, sulfa-Michael/Mannich and some sulfa-Michael triggered multi-step processes. Moreover, some reaction mechanisms and derivatization experiments are introduced appropriately. |
Databáze: | OpenAIRE |
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