| Autor: |
Kyung-Soon Park, Seong-Jin Kim, Sohyun Hwang, Eunbyeol Lee, Hyung-Keun Kim, Kwang-Soo Kim, Ji-Hoon Park, Nuri Oh, Hyeon-Ju Cho |
| Rok vydání: |
2023 |
| DOI: |
10.1158/1541-7786.22512525.v1 |
| Popis: |
Figure S1. (A) Quantified presentation of ZEB1, ELK3 and CDH1 expression with the dataset of 49 breast cancer cell lines obtained from the University of California Santa Cruz (UCSC) Xena Browser (http://xena.ucsc.edu/). (B) Correlation efficiency analysis of ZEB1/ELK3, CHD1/ELK3 and CDH1/ZEB1 expression in 49 breast cancer cell lines. The data of triple negative breast cancer cell lines are presented as grey color. Figure S2. Correlation analysis of ELK3 and ZEB1 protein expression in 6 breast cell lines of figure 1C. Immunoblot band intensity of ELK3 and ZEB1 is normalized to that of GAPDH. The data of basal type of breast cancer cell lines are presented as red dots. Figure S3. The effect of ELK3 suppression on the expression of EMT-related transcription factors. Figure S4. Survival analysis mediated by the expression of ELK3 and ZEB1. Figure S5. The transcriptional repressor activity of the ELK3 deletion mutant on the E-cadherin promoter. Figure S6. ZEB1-independent transcriptional repressor activity of ELK3 on the E-cadherin promoter. Figure S7. Correlation of ELK3 and other EMT related transcription factors in breast cancer patients. The Cancer Genome Atlas (TCGA) database was analyzed by GenExMiner 3.0. Table S1. Plasmids used in this study Table S2. siRNAs used in this study Table S3. Oligomers used in this study Table S4. Antibodies used in this study |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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