Augmented Very Low Frequency Component of Heart Rate Variability During Obstructive Sleep Apnea
| Autor: | Ryujiro Sasanabe, Masato Maekawa, Christian Guilleminault, Toshiaki Shiomi, Izumi Hirota, Tadashi Kobayashi |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Male Valsalva Maneuver Polysomnography Body Mass Index Hypoxemia Sleep Apnea Syndromes Heart Rate Physiology (medical) Heart rate Humans Heart rate variability Medicine Dentures Aged Sleep disorder medicine.diagnostic_test business.industry Middle Aged medicine.disease Obstructive sleep apnea Pulse oximetry Anesthesia Female Neurology (clinical) medicine.symptom Pulmonary Ventilation business Electrocardiography |
| Zdroj: | Sleep. 19:370-377 |
| ISSN: | 1550-9109 0161-8105 |
| DOI: | 10.1093/sleep/19.5.370 |
| Popis: | After documenting the presence of obstructive sleep apnea syndrome (OSAS) through polysomnographic monitoring, we performed simultaneous ambulatory recordings of electrocardiogram, oronasal airflow, and pulse oximetry on 12 OSAS patients with normal autonomic nervous function for a period of 24 hours. The power spectrum of heart rate variability was investigated before and during treatments using dental appliances. Freuquency domain analysis showed that the very low frequency component of heart rate (0.008-0.04 Hz) was increased in OSAS patients and that a very low frequency peak appeared during episodes of obstructive sleep apnea. The increase in very low frequency identification was synchronized with episodes of absence of air exchange or hypoxemia (decreased arterial oxygen saturation) that occurred repeatedly at a cycle length of 25-120 seconds in our subjects. Frequency domain analysis of heart rate variability before and during prosthetic mandibular advancement treatment showed that only the very low frequency was significantly decreased during prosthetic mandibular advancement treatment, whereas the other frequencies, i.e. high, low, and ultralow frequency component values, showed no significant changes. Time domain analysis of heart rate variability before and during prosthetic mandibular advancement treatment showed no significant changes in any of these parameters. Frequency domain analysis of heart rate variability during nocturnal sleep, especially investigation of very low frequency and very low frequency peak, can be a noninvasive low-cost approach to diagnose and even better monitor subjects undergoing treatment at home, particularly considering that R-R intervals can be extracted from pulse oximetry and that analysis software programs are already commercially available. |
| Databáze: | OpenAIRE |
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