Are the definitions for chronic diarrhoea adequate? Evaluation of two different definitions in patients with chronic diarrhoea
| Autor: | Antal Bajor, Magnus Simren, Hasse Abrahamsson, Anders Kilander, Riadh Sadik, Per-Ove Stotzer, Henrik Sjövall |
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| Rok vydání: | 2015 |
| Předmět: |
Stool consistency
Pediatrics medicine.medical_specialty business.industry digestive oral and skin physiology Gastroenterology Chronic diarrhoea medicine.disease chemistry.chemical_compound Bloating Microscopic colitis Oncology chemistry Medicine Stool frequency In patient SeHCAT business Gastrointestinal endoscopy |
| Zdroj: | United European Gastroenterology Journal. 3:381-386 |
| ISSN: | 2050-6414 2050-6406 |
| DOI: | 10.1177/2050640615580219 |
| Popis: | The classical definition of chronic diarrhoea is ≥3 defecations/day, with a stool weight of more than 200 g and duration of ≥4 weeks. However, with this definition many patients with substantial symptoms and pathology will be excluded from further investigations. As a consequence other definitions have been proposed, mainly based on evaluation of the stool form.To evaluate the accuracy of the classic criteria for diarrhoea in comparison with a definition based on stool consistency, using the Bristol Stool Form Scale.All patients were investigated with laboratory tests, upper and lower gastrointestinal endoscopy with biopsies, and SeHCAT test. They were asked to complete a diary recording stool frequency and consistency during a week, as well as other gastrointestinal symptoms (pain, bloating and gas).One hundred and thirty-nine subjects were eligible for analysis. Ninety-one had an organic cause of diarrhoea. Fifty-three patients had ≥3 loose stools/day, whereas 86 reported3 stools/day. Ninety had a median stool consistency that was mushy or loose and 49 had harder stools. A higher proportion of subjects with an organic cause of their diarrhoea compared with subjects with a functional bowel disorder had ≥3 loose stools/day, 43/91 (47%) vs. 10/48 (21%) (p 0.01). Similarly, more subjects with an organic cause of their diarrhoea versus patients with a functional bowel disorder had a median stool consistency that was mushy or watery, 73/91 (80%) vs. 17/48 (35%), p 0.0001. When diarrhoea was defined according to stool form, more patients were classified correctly as having a functional disorder or organic disorder, compared with the classical definition (p 0.05).Loose stools defined according to the Bristol Stool Form scale seem to be the best predictor of having an organic cause of the diarrhoea. |
| Databáze: | OpenAIRE |
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