| Autor: |
Douglas D. Thomas, Benjamin A. Garcia, Mark Maienschein-Cline, Xing-Jun Cao, Pinal Kanabar, Neil Bahroos, Lin L. Mantell, Vy Pham, Rhea C. Bovee, Jason R. Hickok, Divya Vasudevan |
| Rok vydání: |
2023 |
| Popis: |
Supplementary Materials and Methods. Figure S1. Nitric oxide induces significant changes in histone posttranslational modifications. Figure S2. NO-mediated gene expression changes are consistent with the induction of an oncogenic phenotype. Figure S3. Nitric oxide alters the distribution patterns of H3K9ac and H3K9me2 across the genome. Figure S4. NO-upregulated genes with a new promoter-associated H3K9ac peak are involved in critical tumorigenic pathways. Table S1. NO-mediated changes in global levels of histone acetylation. Table S2. List of NO-regulated miRNAs (1.5 Fold Change cut-off). Table S3. Control ChIP-PCR primer sequences. Table S4. List of transcription factors with binding motifs found exclusively around promoters of upregulated genes with a new NO-induced H3K9ac peak. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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