Structural brain correlates of adolescent resilience

Autor:	Tomáš Paus, Bernd Ittermann, Trevor W. Robbins, Patricia J. Conrod, Mira Fauth-Bühler, Arun L.W. Bokde, Uli Bromberg, Andreas Ströhle, Gunter Schumann, Hugh Garavan, Michael N. Smolka, Penny A. Gowland, Christian Büchel, Juergen Gallinat, Keith B. Burt, Herta Flor, André Galinowski, Karl Mann, Tobias Banaschewski, Robert Whelan, Zdenka Pausova, Marcella Rietschel, Andreas Heinz, Frauke Nees, Luise Poustka, Gareth J. Barker, Dimitri Papadopoulos-Orfanos
Rok vydání:	2016
Předmět:	Male Adolescent media_common.quotation_subject competence IMAGEN study Prefrontal Cortex Grey matter Imaging Adaptive functioning Developmental psychology 03 medical and health sciences 0302 clinical medicine Adaptation Psychological Developmental and Educational Psychology medicine Personality Humans Academic competence Prefrontal cortex resilience Competence (human resources) adversity media_common Operationalization Resilience Psychological 030227 psychiatry Europe Psychiatry and Mental health medicine.anatomical_structure Pediatrics Perinatology and Child Health adolescence Social competence Female Psychology 030217 neurology & neurosurgery Stress Psychological
Zdroj:	Burt, K B, Whelan, R, Conrod, P J, Banaschewski, T, Barker, G J, Bokde, A L W, Bromberg, U, Büchel, C, Fauth-Bühler, M, Flor, H, Galinowski, A, Gallinat, J, Gowland, P, Heinz, A, Ittermann, B, Mann, K, Nees, F, Papadopoulos-Orfanos, D, Paus, T, Pausova, Z, Poustka, L, Rietschel, M, Robbins, T W, Smolka, M N, Ströhle, A, Schumann, G & Garavan, H 2016, ' Structural brain correlates of adolescent resilience ', Journal of Child Psychology and Psychiatry, vol. 57, no. 11, pp. 1287-1296 . https://doi.org/10.1111/jcpp.12552
ISSN:	1469-7610
DOI:	10.1111/jcpp.12552
Popis:	Background: Despite calls for integration of neurobiological methods into research on youth resilience (high competence despite high adversity), we know little about structural brain correlates of resilient functioning. The aim of the current study was to test for brain regions uniquely associated with positive functioning in the context of adversity, using detailed phenotypic classification. Methods: 1,870 European adolescents (Mage = 14.56 years, SDage = 0.44 years, 51.5% female) underwent MRI scanning and completed behavioral and psychological measures of stressful life events, academic competence, social competence, rule-abiding conduct, personality, and alcohol use. Results: The interaction of competence and adversity identified two regions centered on the right middle and superior frontal gyri; grey matter volumes in these regions were larger in adolescents experiencing adversity who showed positive adaptation. Differences in these regions among competence/adversity subgroups were maintained after controlling for several covariates and were robust to alternative operationalization decisions for key constructs. Conclusions: We demonstrate structural brain correlates of adolescent resilience, and suggest that right prefrontal structures are implicated in adaptive functioning for youth who have experienced adversity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985c7ed77ca72a843da2f8b39c5bd41c https://pubmed.ncbi.nlm.nih.gov/27859344 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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