Prenatal diagnosis of fetal respiratory function: evaluation of fetal lung maturity using lung‐to‐liver signal intensity ratio at magnetic resonance imaging
| Autor: | T. Waseda, S. Makinoda, C. Sasakura, Y. Watanabe, Y. Oka, Ryota Fujii, Mosfequr Rahman |
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| Rok vydání: | 2014 |
| Předmět: |
Pathology
medicine.medical_specialty Prenatal diagnosis Pregnancy Prenatal Diagnosis Humans Medicine Respiratory function Lung Genetics (clinical) Retrospective Studies Fetus Receiver operating characteristic medicine.diagnostic_test business.industry Obstetrics and Gynecology Gestational age Magnetic resonance imaging Original Articles Magnetic Resonance Imaging Respiratory Function Tests Fetal Diseases medicine.anatomical_structure Liver Gestation Female Respiratory Insufficiency business Nuclear medicine |
| Zdroj: | Prenatal Diagnosis |
| ISSN: | 1097-0223 0197-3851 |
| DOI: | 10.1002/pd.4469 |
| Popis: | Objective The purpose of this retrospective study is to determine the fetal lung-to-liver signal intensity ratio (LLSIR) on T2-weighted images for the prediction of neonatal respiratory outcome. Methods One hundred ten fetuses who underwent magnetic resonance imaging (MRI) examination for various indications after 22 weeks of gestation participated in this study. LLSIR was measured as the ratio of signal intensities of the fetal lung and liver on T2-weighted images at MRI. We examined the changes of the ratio with advancing gestation and the relations between LLSIR and the presence of the severe respiratory disorder (SRD) after birth. The best cut-off value of the LLSIR to predict respiratory outcome after birth was calculated using receiver operating characteristic (ROC) curve analysis. Results Lung-to-liver signal intensity ratio correlated significantly with advancing gestational age (R = 0.35, p |
| Databáze: | OpenAIRE |
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