Dermatologic toxicities of targeted antineoplastic agents and immune checkpoint inhibitor therapy in pediatric patients: A systematic review
| Autor: | Lucy Y. Liu, Jenna Strelo, Bernice Y. Kwong, Joyce M.C. Teng, Sheri L. Spunt, Lisa C. Zaba |
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| Rok vydání: | 2021 |
| Předmět: |
Oncology
medicine.medical_specialty Immune checkpoint inhibitors medicine.medical_treatment Antineoplastic Agents Timely diagnosis Targeted therapy Neoplasms Internal medicine medicine Pediatric oncology Humans Child Adverse effect Immune Checkpoint Inhibitors Skin business.industry Cancer Hematology Immunotherapy medicine.disease Pediatrics Perinatology and Child Health Quality of Life Dose reduction business |
| Zdroj: | Pediatric Blood & Cancer. 68 |
| ISSN: | 1545-5017 1545-5009 |
| Popis: | Cutaneous adverse events (cAEs) from targeted antineoplastic agents and immune checkpoint inhibitors are common in children with cancer and may lead to dose reduction or cessation of critical oncologic treatment. Timely diagnosis and proper management of cAEs in pediatric oncology patients is essential to optimize ongoing cancer-directed therapy and improve quality of life. This systematic review of published studies summarizes dermatologic toxicities to targeted anticancer treatments and immune checkpoint inhibitors. |
| Databáze: | OpenAIRE |
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