Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality

Autor:	Alfredo Chiappe, Joseph R. Zunt, Jorge Gallardo, Jaime Soria, Andres G. Lescano
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	0301 basic medicine leukocyte count Pediatrics antibiotic resistance time to treatment Hospitalized patients retrospective study Human immunodeficiency virus (HIV) ethambutol rifampicin medicine.disease_cause 0302 clinical medicine 030212 general & internal medicine altered state of consciousness fever therapy delay adult risk assessment meningitis cohort analysis aged hospital patient female Infectious Diseases AcademicSubjects/MED00290 risk factor Oncology tuberculosis young adult disease severity headache Meningitis hospitalization survival rate isoniazid medicine.medical_specialty pyrazinamide Tuberculosis antiretroviral therapy prevalence 030106 microbiology dexamethasone Article Tuberculous meningitis 03 medical and health sciences male Disease severity Human immunodeficiency virus infection medicine cross-sectional study human drug sensitivity cerebrospinal fluid analysis hospital mortality business.industry human cell Mycobacterium tuberculosis virus load medicine.disease mortality antibiotic sensitivity tuberculous meningitis Poisson distribution observational study Brief Reports multidrug resistant tuberculosis business
Zdroj:	Open Forum Infectious Diseases
ISSN:	2328-8957
Popis:	We conducted a retrospective cross-sectional study of adult hospitalized patients with confirmed tuberculous meningitis to determine the impact of the timing of treatment initiation on mortality. The mortality of tuberculous meningitis patients was high and was associated with delay in initiation of treatment, older age, HIV infection, and higher disease severity at admission.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9784a7193163f4826af15149d2924b81 http://europepmc.org/articles/PMC8297700 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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