Intra-arterial steroid-injection therapy for steroid-refractory acute graft-versus-host disease with the evaluation of angiography
| Autor: | Yuji Kishimoto, Masahiro Fujimoto, N Tanigawa, Kenichirou Tajima, Katsuhiro Zen, Noriaki Matsumoto, Ryuichi Amakawa, Shosaku Nomura, S. Fukuhara, K Nakai, S Sawada |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Drug Resistance Graft vs Host Disease Hematopoietic stem cell transplantation Route of administration immune system diseases hemic and lymphatic diseases medicine Humans Mesenteric arteries Transplantation integumentary system medicine.diagnostic_test business.industry Liver Diseases Angiography Hematopoietic Stem Cell Transplantation Hematology Middle Aged Hematologic Diseases Surgery Intestinal Diseases surgical procedures operative medicine.anatomical_structure Injections Intra-Arterial Circulatory system Acute Disease Female Steroids Complication business Blood vessel Artery |
| Zdroj: | Bone marrow transplantation. 33(12) |
| ISSN: | 0268-3369 |
| Popis: | We treated three patients with steroid-refractory acute graft-versus-host disease (aGVHD) with intra-arterial steroid-injection therapy (IAST). Two patients with gut aGVHD received IAST into both superior and inferior mesenteric arteries, while one patient with liver aGVHD received IAST into the proper hepatic artery. The volume of stools and the bilirubin level improved soon after IAST. Angiography of the superior and inferior mesenteric arteries was performed in the two patients with steroid-refractory gut aGVHD, and identical abnormal findings were obtained. IAST might be an earlier option for steroid-refractory aGVHD. |
| Databáze: | OpenAIRE |
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