Isolation and identification of compounds from Phaleria macrocarpa (Scheff.) Boerl fruit extract
| Autor: | James M. Sinambela, Ujiatmi Dwi Marlupi, Raymond R. Tjandrawinata, Emanuel Dani Ramdani |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
lcsh:Arctic medicine. Tropical medicine
Dried fruit lcsh:RC955-962 Ethyl acetate Glyceryl pentacosanoate 01 natural sciences Biochemistry Genetics and Molecular Biology (miscellaneous) 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Phaleria macrocarpa Botany 1 6 7-Trihydroxy-3-methoxyxanthone lcsh:QH301-705.5 Ethanol Chromatography biology biology.organism_classification 0104 chemical sciences 010404 medicinal & biomolecular chemistry chemistry Heteronuclear molecule lcsh:Biology (General) Stationary phase 030220 oncology & carcinogenesis Proton NMR Mass spectrum 1 7-Dihydroxy-3 6-dimethoxyxanthone |
| Zdroj: | Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 4, Pp 300-305 (2017) |
| ISSN: | 2221-1691 |
| Popis: | Objective To identify and isolate the chemical compounds of Phaleria macrocarpa (P. macrocarpa) fruit ethanolic extract. Methods Dried fruit of P. macrocarpa was extracted with 90% ethanol and partitioned between n-hexane/H2O and ethyl acetate/H2O. The organic layer was fractionated by various stationary phase and identified by using combined data of 1D [(proton nuclear magnetic resonance (NMR), carbon-13 NMR)], 2D-NMR (heteronuclear multiple-quantum correlation and heteronuclear multiple-bond correlation), and mass spectrum. Results Purification of n-hexane and ethyl acetate fractions from ethanolic extract of P. macrocarpa fruit resulted in isolation of nine compounds. Conclusions A new compound was isolated and identified as glyceryl pentacosanoate. Also, two xanthones, which are 1,7-dihydroxy-3,6-dimethoxyxanthone and 1,6,7-trihydroxy-3-methoxyxanthone, are firstly reported to be isolated from P. macrocarpa. |
| Databáze: | OpenAIRE |
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