Photophysical properties and theoretical photosensitization mechanism of non-peripherally dodecyloxy substituted metallophthalocyanines for photodynamic therapy
| Autor: | M. Murali Krishnan, M. N. Arumugham, S. Baskaran |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Absorption spectroscopy
Chemistry medicine.medical_treatment chemistry.chemical_element Photodynamic therapy 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology Photochemistry 01 natural sciences Copper Fluorescence humanities 0104 chemical sciences Inorganic Chemistry chemistry.chemical_compound Nickel Monomer medicine Phthalocyanine Physical and Theoretical Chemistry 0210 nano-technology Photodegradation |
| DOI: | 10.6084/m9.figshare.12936896.v1 |
| Popis: | Non-peripherally tetradodecyloxy substituted copper (CuPc 3) and nickel (NiPc 4) phthalocyanines and the compounds were synthesized. The absorption spectra of synthesized Pcs were showed monomeric behavior evidenced by a narrow between 680 and 750 nm (Q band) for CuPc(3) and NiPc(4) in different solvents. The fluorescence behavior of the Pcs was studied in chloroform. The CuPc (3) showed outstanding stability in THF as solvent during photodegradation studies. The possible photodynamic therapy reaction mechanisms were studied through the calculation of ionization potentials and electron affinity in both vacuum and solvents using SCRF model. |
| Databáze: | OpenAIRE |
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