Synthesis and characterization of Au and Bi2O3 decorated Fe3O4@PAMAM dendrimer nanocomposites for medical applications
Autor: | Nurdan Kurnaz Yetim, Mümin Mehmet Koç, Fatma Kurşun Baysak, Dilek Nartop |
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Přispěvatelé: | [Belirlenecek] |
Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Nanostructure
Nanocomposite Materials science Composite number Bi2O3 Fe3O4 TEOS Nanochemistry Nanoparticle Nanotechnology 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology PAMAM dendrimers 01 natural sciences 0104 chemical sciences Magnetic hyperthermia Chemistry (miscellaneous) Magnetic nanoparticles Au Fourier transform infrared spectroscopy 0210 nano-technology X-ray tomography Medical applications Superparamagnetism |
Popis: | Fe3O4 magnetic nanoparticles were produced and covered with TEOS and APTES which were known to reduce the toxic properties of nanoparticles. Nanoparticles were functionalized second-generation PAMAM dendrimers and doped with Au and Bi2O3 nanoparticles where Fe3O4@G2/Au/Bi2O3 nanocomposites were obtained for potential multimodal imaging applications. Physicals structures of the nanocomposites were characterized using SEM and TEM which illustrate that nanoparticles were in composite form. Chemical composition of nanostructures was confirmed using EDX and FTIR. Magnetic characteristics were checked using VSM. It was seen that nanoparticles have superparamagnetic properties which indicate that nanocomposites have potential to be used in MRI and magnetic hyperthermia applications. X-ray imaging properties were confirmed using X-ray imaging and CT imaging. It was confirmed that doping nanoparticles with Au and Bi2O3 nanoparticles significantly enhanced the X-ray tomography contrast enhancement properties which illustrate the theranostic properties of the nanocomposites. Duzce University Scientific Research Project CommissionDuzce University [2019.07.06.981] This work was supported by Duzce University Scientific Research Project Commission with project number 2019.07.06.981. We also would like to thank Mr. Gokhan AYDEGER for his valuable contributions. WOS:000615754700001 |
Databáze: | OpenAIRE |
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