Frequency of Hypomagnesaemia following Total and Near-total Thyroidectomy and its relationship with Hypocalcaemia
| Autor: | Tasleem Akhtar, Nadeem Ikram, Sana Viqar, Naeem Zia |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
musculoskeletal diseases
endocrine system diseases Cross-sectional study medicine.medical_treatment Signs and symptoms Postoperative Complications medicine Humans Magnesium Pakistan Hypocalcaemia In patient Hypocalcemia business.industry Thyroidectomy nutritional and metabolic diseases General Medicine Magnesium level medicine.disease Near total thyroidectomy Exact test Cross-Sectional Studies Anesthesia Calcium business |
| Zdroj: | Journal of the College of Physicians and Surgeons Pakistan. 31:571-575 |
| ISSN: | 1681-7168 1022-386X |
| DOI: | 10.29271/jcpsp.2021.05.571 |
| Popis: | Objective To determine the frequency of hypomagnesaemia in patients undergoing thyroidectomy and evaluate its relationship with postoperative hypocalcaemia. Study design Observational, cross-sectional study. Place and duration of study Surgical Unit 1, Benazir Bhutto Hospital, Rawalpindi, Pakistan from April 2017 to May 2019. Methodology Preoperative and 24-hour postoperative samples for serum calcium and magnesium of 75 patients undergoing total and near-total thyroidectomy were taken. Postoperative signs and symptoms of hypocalcaemia were documented. Data was analysed on SPSS version 22, using independent and paired t-test, Pearson correlation, linear regression, Chi-square test and Fisher's Exact test. Results Postoperatively 49 (65.3%) patients developed hypocalcaemia and 8 (10.7%) developed hypomagnesaemia. Postoperative hypocalcaemia was significantly associated with hypomagnesaemia (p=0.03) with a significant positive linear correlation. Ten patients (13.3%) developed symptomatic hypocalcaemia; however, it was not associated with postoperative hypomagnesaemia. Postoperative hypocalcaemia and hypomagnesaemia were significantly associated with preoperative calcium level (p = 0.03 and 0.04, respectively). There was significantly lower calcium level in patients with hypomagnesaemia (p = 0.002) and a significant fall in magnesium level in patients developing hypocalcaemia (p = 0.044). Conclusion Postoperatively hypocalcaemia was prevalent following thyroidectomy, while hypomagnesaemia was not common. Hypomagnesaemia and a fall in magnesium level after surgery was associated with hypocalcaemia; but not with symptomatic hypocalcaemia. Monitoring of magnesium levels in severe or persistent hypocalcaemia is recommended. While this study proves a relationship between calcium and magnesium, its clinical implication must be further studied. Key Words: Calcium, Magnesium, Postoperative, Hypocalcaemia, Hypomagnesaemia, Thyroidectomy. |
| Databáze: | OpenAIRE |
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