A new homeo-box is present in overlapping cosmid clones which define the mouse Hox-1 locus
| Autor: | Brigitte Galliot, Philippe Mähl, Agnès Baron, Denis Duboule |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1986 |
| Předmět: |
Embryo
Nonmammalian Transcription Genetic Xenopus Inbred Strains Sequence Homology Locus (genetics) Mice Inbred Strains Biology General Biochemistry Genetics and Molecular Biology Nucleic acid thermodynamics Mice Fetus Species Specificity Genetic Pregnancy Sequence Homology Nucleic Acid Gene expression Animals Humans Cloning Molecular Teratoma/genetics Hox gene Molecular Biology Gene Genetics Nonmammalian General Immunology and Microbiology Base Sequence Nucleic Acid General Neuroscience Mammalian Drosophila/genetics Protein primary structure Teratoma Molecular Nucleic Acid Hybridization DNA Restriction Enzymes Embryo Mammalian Cosmids Teratocarcinoma Embryo Cosmid Drosophila Female Transcription Research Article Cloning |
| Zdroj: | EMBO Journal, Vol. 5, No 8 (1986) pp. 1973-1980 Scopus-Elsevier Europe PubMed Central |
| ISSN: | 0261-4189 |
| Popis: | A new murine homeo-box (Hox1-3) has been isolated and studied with respect to its structure and transcriptional pattern. This homeo-box is part of a gene which is specifically regulated during mouse prenatal development and expressed in a restricted number of teratocarcinoma tumours as well as in adult testis. Hox1-3 is shown to be a member of a cluster of at least four homeo-boxes lying within a 75-kb segment of DNA on mouse chromosome 6. The structure of the whole cluster, the Hox-1 locus is presented. |
| Databáze: | OpenAIRE |
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