Biomonitorización de la exposición a contaminantes ambientales en recién nacidos y sus progenitores en Madrid [BioMadrid]: diseño del estudio y resultados del trabajo de campo
Autor: | Elisa Gil, José Miguel García-Sagredo, Pedro Arias, Beatriz Pérez-Gómez, Margot Cisneros, Gonzalo López-Abente, Mercedes Martínez, María José González, América de León, Mario Antonio Fernández, Marina Pollán, J. Sanz, Concha de Paz, Nuria Aragonés, Andrés Iriso, Amparo de Santos, Jenaro Astray, Ana María Pérez-Meixeira, José Frutos García, Ángel Asensio |
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Přispěvatelé: | Instituto de Salud Carlos III |
Rok vydání: | 2008 |
Předmět: |
Adult
Male Parents Adolescent Urban Population Population Pilot Projects Cohort Studies Pregnancy Environmental health Surveys and Questionnaires Biomonitoring Humans Adults education Child Environmental biomonitoring Pollutant education.field_of_study Micronucleus Tests Public Health Environmental and Occupational Health Infant Newborn Infant Heavy metals Study design Environmental Exposure Middle Aged Metropolitan area Childhood Pilots Geography Work (electrical) Socioeconomic Factors Spain Exposure assessment Population study Feasibility Studies Residence Environmental Pollutants Female Public Health Biomarkers Environmental Monitoring |
Zdroj: | Gaceta Sanitaria v.22 n.5 2008 SciELO España. Revistas Científicas Españolas de Ciencias de la Salud instname Repisalud Instituto de Salud Carlos III (ISCIII) ResearcherID |
Popis: | In Spain environmental surveillance has mainly relied on measures of selected pollutants in air, water, food and soil. A study was conducted in Madrid to assess the feasibility of implementing a surveillance system of exposure among the general population to specific environmental pollutants, using bio-markers. The project was basically focused on the environment surrounding newborns. Hence, the study population was made up of 145 triplets of pregnant women at around 8 months' gestation, their partners, and newborns from two areas, representing the two main types of urban environments in the region, i.e., the City of Madrid and its outlying metropolitan belt. Multiple biologic substrates were collected from each participant in order to assess the most suitable samples for an environmental surveillance system. The selected contaminants represent the main agents to which a population like that of Madrid is exposed every day, including certain heavy metals, persistent organic pollutants and polycyclic aromatic hydrocarbons, as well as micronuclei in peripheral blood, a commonly used unspecific index of cytogenetic damage. In addition, passive air samplers were placed around subjects' place of residence. This paper reports in detail on the design and response rates, summarizes field work results, and discusses some lessons learned. Financial support was obtained from the Madrid Regional Health & Consumer Affairs Authority and the Spanish Health Research Fund (Fondo de Investigación Sanitaria [FIS]) grant PI040777. Sí |
Databáze: | OpenAIRE |
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