Magnetic Scaffolds Enriched with Bioactive Nanoparticles for Tissue Engineering
| Autor: | Hadas Skaat, Ofra Ziv-Polat, Abraham Shahar, David Last, Yael Mardor, Shlomo Margel |
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| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_treatment
Biomedical Engineering Pharmaceutical Science Maghemite Nanoparticle Materials testing engineering.material Conjugated system Ferric Compounds Fibrin Biomaterials Magnetics Tissue engineering Materials Testing medicine Animals Cell Aggregation Tissue Engineering biology Chemistry Growth factor equipment and supplies Rats Rats Inbred Lew engineering biology.protein Nanoparticles Biomedical engineering |
| Zdroj: | Advanced Healthcare Materials. 1:168-171 |
| ISSN: | 2192-2640 |
| DOI: | 10.1002/adhm.201100056 |
| Popis: | Novel magnetic fibrin hydrogel scaffolds for cell implantation and tissue engineering are reported. The magnetic scaffolds are produced by the interaction between thrombin-conjugated maghemite nanoparticles of narrow size distribution and fibrinogen. These scaffolds, enriched with growth factor conjugated fluorescent maghemite nanoparticles, provide a supporting 3D environment for massive proliferation of various cell types, and can be successfully visualized by MRI. |
| Databáze: | OpenAIRE |
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