High mean platelet volume-to-platelet count ratio as a diagnostic maker for increased risk of liver function damage in pediatric patients with infectious mononucleosis in China

Autor:	Xiucui Han, Junfeng Zhang, Yong-xia Liu, Hui Xu, Xiuzhi Duan, Pengfei Xu
Rok vydání:	2019
Předmět:	0301 basic medicine Cancer Research medicine.medical_specialty digestive system Gastroenterology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Immunology and Microbiology (miscellaneous) Internal medicine White blood cell Medicine Platelet Mean platelet volume Creatinine business.industry Platelet Distribution Width Articles General Medicine digestive system diseases 030104 developmental biology medicine.anatomical_structure chemistry 030220 oncology & carcinogenesis Uric acid Liver function Hemoglobin business
Zdroj:	Experimental and therapeutic medicine. 18(6)
ISSN:	1792-0981
Popis:	The aim of the present study was to provide novel laboratory indexes for infectious mononucleosis (IM) in pediatric patients. In the present prospective study, a total of 141 pediatric patients with IM and 146 healthy subjects were enrolled. The white blood cell count (WBC), red blood cell count (RBC), hemoglobin (HB), platelet count (PLT), mean platelet volume (MPV), platelet distribution width (PDW), alanine aminotransferase (ALT), aspartate aminotransferase (AST), γ-glutamyl transferase (GGT), uric acid (UA), urea, creatinine, total cholesterol (TC) and triglycerides (TG) in peripheral blood were evaluated. WBC, ALT, AST, GGT, UA, TG, MPV and the MPV/PLT ratio in the patients were significantly higher compared with those in the controls (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967cd4d66f32820b293800770f170501 https://pubmed.ncbi.nlm.nih.gov/31777555 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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