Evaluation of choroidal layer thickness in central serous chorioretinopathy
| Autor: | Elon H. C. van Dijk, Jay Chhablani, Pooja H. Mehta, Camiel J. F. Boon, Catherine B. Meyerle, Asiya Jabeen, Momin Ansari, Bindu Rajesh, Ayesha Jabeen, Sunila Dumpala, Lihteh Wu, Chintan Sarvaiya, Shilpi Shah, Alay S. Banker, Daren Hanumunthadu |
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| Přispěvatelé: | Ophthalmology, ANS - Complex Trait Genetics |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
genetic structures Chronic central serous chorioretinopathy lcsh:Ophthalmology Optical coherence tomography Ophthalmology medicine medicine.diagnostic_test business.industry Choroid Significant difference Layer thickness eye diseases Serous fluid Central Serous Chorioretinopathy Optical Coherence Tomography medicine.anatomical_structure lcsh:RE1-994 Original Article Enhanced depth imaging Thickening sense organs business |
| Zdroj: | Journal of Ophthalmic and Vision Research, 14(2), 164-170. Wolters Kluwer Medknow Publications Journal of Ophthalmic & Vision Research Journal of Ophthalmic & Vision Research, Vol 14, Iss 2, Pp 164-170 (2019) Journal of Ophthalmic and Vision Research, 14(2), 164-170 |
| ISSN: | 2008-2010 |
| Popis: | Purpose: To evaluate medium and large choroidal vessel layer thickness (MCVT and LCVT, respectively) in eyes with acute and chronic central serous chorioretinopathy (CSC) in comparison with age-matched controls. Methods: The study included 96 eyes of 96 patients with CSC, including 53 eyes with acute CSC, 43 eyes with chronic CSC, and 30 eyes of 30 age-matched normal subjects. Manual measurements of subfoveal choroidal thickness (SFCT), MCVT, and LCVT at subfoveal and 750 μm nasal and temporal to the fovea locations were made on enhanced depth imaging optical coherence tomography (EDI-OCT) of the macula in all subjects using ImageJ software (National Institutes of Health, Bethesda, MD, USA). Results: SFCT in acute CSC was significantly larger than that in healthy eyes (P = 0.0001). SFCT in acute CSC did not differ significantly from that in chronic CSC eyes. Subfoveal LCVT and MCVT in acute CSC eyes were greater than those in healthy eyes (P = 0.02 and P = 0.03, respectively). Mean SFCT and MCVT in chronic CSC eyes were significantly larger than those in control eyes (P = 0.01 and P = 0.04, respectively). No significant difference in LCVT was observed between chronic and control eyes. Conclusion: Choroidal vasculature is altered in both acute and chronic CSC. SFCT, MCVT, and LCVT are higher in eyes with acute CSC. The thickening of medium choroidal vessels is still detectable in chronic CSC compared to control eyes. |
| Databáze: | OpenAIRE |
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