Liver Size, Bodyweight, and Tolerance to Acute Complete Occlusion of Congenital Extrahepatic Portosystemic Shunts in Dogs
| Autor: | Toby G Knowles, Frances J. Barr, Peter E. Holt, Alasdair Hotston Moore, Ivan Doran |
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| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Portal venous pressure Congenital Abnormalities Cohort Studies Dogs Internal medicine Hypertension Portal Complete occlusion Occlusion medicine Animals Clinical significance Dog Diseases Longitudinal Studies Ultrasonography General Veterinary Portal Vein business.industry Body Weight Organ Size Oxygenation Surgery Portal System Catheter Treatment Outcome Liver Cardiology Female Portosystemic shunt Ligation business |
| Zdroj: | Veterinary Surgery. 37:656-662 |
| ISSN: | 1532-950X 0161-3499 |
| Popis: | To investigate the relationship between preoperative liver size, bodyweight, and tolerance to shunt occlusion in dogs with congenital extrahepatic portosystemic shunt(s) (CPSS).Longitudinal cohort study.Dogs with CPSS (n=35).Ultrasonography was used to measure preoperative maximum transverse dimension of the liver (TS) of each dog. Intraoperative portal pressures were measured, before and after CPSS occlusion, via a jejunal vein catheter. Tolerance to shunt occlusion was judged on gross visceral observations, and on changes in portal pressure, central venous and mean arterial pressures.TS was significantly related to bodyweight (P.05). Mean ratios for TS/bodyweight were calculated for dogs tolerant and intolerant of acute complete shunt occlusion. Dogs tolerant to occlusion had significantly higher TS/bodyweight ratios than dogs intolerant to occlusion (P=.025). Dogs with a TS/bodyweight ratio of7 were more likely to tolerate CPSS occlusion than dogs with a TS/bodyweight ratio of5 (P=.036). A model was generated to predict portal pressure rise after shunt occlusion, based on liver dimensions and bodyweight (R=0.668). Intestinal oxygenation did not correlate significantly with tolerance to CPSS occlusion (P=.29).In dogs with CPSS, liver size (relative to bodyweight) is significantly greater (P=.025) in dogs that are tolerant of full ligation than intolerant of occlusion.Preoperative measurement of bodyweight and liver size help indicate the likelihood of tolerance to acute complete occlusion of CPSS in dogs. |
| Databáze: | OpenAIRE |
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