Validation of NoSAS score for screening of sleep-disordered breathing in a multiethnic Asian population
Autor: | Yan Yi Cheung, Chi-Hang Lee, Adeline Tan, Rob M. van Dam, Linda W.L. Tan, Yueheng Hong |
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Rok vydání: | 2016 |
Předmět: |
Male
Pediatrics medicine.medical_specialty Population 03 medical and health sciences 0302 clinical medicine Sleep Apnea Syndromes Asian People Pregnancy Medicine Humans Sleep study education education.field_of_study Singapore business.industry Area under the curve Middle Aged Predictive value Health Surveys 030228 respiratory system Otorhinolaryngology Area Under Curve Cohort Asian population Sleep disordered breathing Female Neurology (clinical) business Sleep 030217 neurology & neurosurgery |
Zdroj: | Sleepbreathing = SchlafAtmung. 21(4) |
ISSN: | 1522-1709 |
Popis: | The NoSAS score was developed to identify subjects at high risk of sleep-disordered breathing (SDB). We aimed to validate the NoSAS score in a multiethnic Asian cohort and compare its performance to the STOP-Bang and Berlin questionnaires. A sample of 242 subjects selected from a population-based cohort in Singapore completed home-based sleep testing with an Embletta device (type 3 monitor). All subjects were given the STOP-Bang and Berlin questionnaires for self-administration prior to the sleep study. The NoSAS score was subsequently calculated based on available demographic data and Berlin questionnaire responses. The prevalence of severe SDB, defined as an apnea-hypopnea index cutoff of ≥30 events/h, was 10.7%. The number of subjects who were classified as high risk by the NoSAS score and STOP-Bang and Berlin questionnaires were 76 (31.4%), 89 (36.8%), and 79 (32.6%), respectively. The sensitivity, specificity, and negative and positive predictive values of the NoSAS score to predict severe SDB were 69.2, 73.1, 95.2, and 23.7%, respectively. The STOP-Bang and Berlin questionnaires performed similarly to the NoSAS score, with area under the curve (AUC) values of all three questionnaires clustered around 0.682–0.748. Compared to the STOP-Bang (94.8%) and Berlin questionnaires (96.3%), the NoSAS score (95.2%) had equally high negative predictive value in ruling out severe SDB. The NoSAS score performed similarly to the STOP-Bang and Berlin questionnaires in a multiethnic Asian cohort. All three questionnaires had high negative predictive values in ruling out severe SDB and may have utility as screening tools. |
Databáze: | OpenAIRE |
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