Reductive Amination of 1-Hydroxy-2-propanone Over Nickel and Copper Catalysts
| Autor: | N. Ruhswurmová, Martin Zapletal, Jiří Trejbal, T. Trégner |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
021110 strategic
defence & security studies 2-aminopropanol Process Chemistry and Technology Hydroxy-2-propanone 0211 other engineering and technologies chemistry.chemical_element lcsh:TP155-156 02 engineering and technology General Chemistry 01 natural sciences Biochemistry Copper Reductive amination reductive amination 010406 physical chemistry 0104 chemical sciences Catalysis dimethylpiperazine Nickel chemistry Organic chemistry 1-hydroxy-2-propanone lcsh:Chemical engineering |
| Zdroj: | Chemical and Biochemical Engineering Quarterly, Vol 31, Iss 4, Pp 455-470 (2018) Chemical and Biochemical Engineering Quarterly Volume 31 Issue 4 |
| ISSN: | 1846-5153 0352-9568 |
| Popis: | The one-step reductive amination of 1-hydroxy-2-propanone (acetol) with ammonia to 2-aminopropanol (2-APOL) over commercial nickel and copper catalysts has been studied in the continuous fixed-bed reactor at the temperature from 130 to 220 °C and different molar ratios of reactants. It was found that the optimal molar ratios of H2/acetol and H2/NH3 regarding the selectivity of 2-APOL were 25 and 1, respectively. The highest selectivity of approx. 45 % to desired 2-APOL at total conversion of acetol was achieved in the presence of the nickel catalyst. Major by-products of amination were cis and trans isomers of 2,5- and 2,6-dimethylpiperazines. Mechanism of the formation of these and other detected and/or potential by-products is discussed. So far, unpublished mass spectra of identified by-products, such as N-substituted dimethylpiperazines or various aminoalcohols, are reported in this paper. This work is licensed under a Creative Commons Attribution 4.0 International License. |
| Databáze: | OpenAIRE |
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